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Biacore t200 surface plasmon resonance system
T200 Surface Plasmon Resonance System, supplied by Biacore, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/t200+surface+plasmon+resonance+system/plasmon+resonance+surface/pm42263918-177-9-8
Average 86 stars, based on 1 article reviews
t200 surface plasmon resonance system - by Bioz Stars, 2026-10
86/100 stars

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SPR Assay:

Article Title: An integrated multitarget screening strategy combining network pharmacology with cell membrane chromatography coupled to high-performance liquid chromatography for identifying candidate antidepressant compounds from Cyperus rotundus L.
Article Snippet: 31 Ethnopharmacological relevance: Cyperus rotundus L. (CR) is a traditional Chinese medicine 32 (TCM) herb that has been used for centuries to soothe the liver, regulate Qi, and relieve 33 emotional distress, with classical indications for “Yu syndrome” encompassing depressive 34 mood, chest distension, and dysphoria.. CR is incorporated into representative TCM formulas 35 targeting depression-related conditions, such as Yueju Pill, substantiating its 36 ethnopharmacological relevance in mood disorder management.. However, its complex 37 chemical composition presents considerable challenges for systematic bioactive compound 38 identification, and the specific antidepressant constituents of CR remain poorly characterized, 39 hindering the elucidation of its antidepressant material basis and the development of related 40 therapeutics.

Article Title: Novel GLP-1RA-like effects of Bafetinib: a preliminary study integrated in vitro screening and in vivo validation.
Article Snippet: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are first-line treatments for type 2 diabetes mellitus and obesity.. Nevertheless, their clinical application is constrained by the adimistration route of subcutaneous injection and the safety concerns including gastrointestinal side effects.Aiming to screen novel compounds with potent GLP-1RA-like activityand good safety, and can be given orally, we performed structure-based virtual screening of a library, subsequent surface plasmon resonance and molecular docking analyses in this study.. The results showed that Bafetinib stood our from the library with high high binding affinity to GLP-1R and great thermal stability.

Article Title: Anti-VEGF antibodies and their uses
Article Snippet: Data were fitted using nonlinear regression with the software GRAPHPAD PRISM (GraphPad, San Diego) and the fold improvement over WT was reported as EC50 wild type/EC50 mutant. .. 10.1.2 BIAcore The binding kinetics and affinity of the antibodies for VEGF (human VEGF-A residues 27-191 of Accession # AAV38412) was determined by using a BIAcore T200 surface plasmon resonance system (BIAcore, GE Healthcare, Piscataway, N.J.). .. Coupling running buffer was HBS-EP+ running buffer (10 mM HEPES, 150 mM sodium chloride, 3 mM EDTA 0.05% P-20, pH 7.4); assay running buffer was HBS-EP+ with 300 mM sodium chloride and 0.1 mg/mL BSA (Sigma A7906).

Article Title: GB20-5A8-31, an anti-TL1A antibody for treating inflammatory bowel disease
Article Snippet: .. The binding affinity between the candidate Abs and TL1A trimers (human, cynomolgus, and rat) was evaluated using a Biacore T200 surface plasmon resonance system. ..

Binding Assay:

Article Title: An integrated multitarget screening strategy combining network pharmacology with cell membrane chromatography coupled to high-performance liquid chromatography for identifying candidate antidepressant compounds from Cyperus rotundus L.
Article Snippet: 31 Ethnopharmacological relevance: Cyperus rotundus L. (CR) is a traditional Chinese medicine 32 (TCM) herb that has been used for centuries to soothe the liver, regulate Qi, and relieve 33 emotional distress, with classical indications for “Yu syndrome” encompassing depressive 34 mood, chest distension, and dysphoria.. CR is incorporated into representative TCM formulas 35 targeting depression-related conditions, such as Yueju Pill, substantiating its 36 ethnopharmacological relevance in mood disorder management.. However, its complex 37 chemical composition presents considerable challenges for systematic bioactive compound 38 identification, and the specific antidepressant constituents of CR remain poorly characterized, 39 hindering the elucidation of its antidepressant material basis and the development of related 40 therapeutics.

Article Title: Novel GLP-1RA-like effects of Bafetinib: a preliminary study integrated in vitro screening and in vivo validation.
Article Snippet: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are first-line treatments for type 2 diabetes mellitus and obesity.. Nevertheless, their clinical application is constrained by the adimistration route of subcutaneous injection and the safety concerns including gastrointestinal side effects.Aiming to screen novel compounds with potent GLP-1RA-like activityand good safety, and can be given orally, we performed structure-based virtual screening of a library, subsequent surface plasmon resonance and molecular docking analyses in this study.. The results showed that Bafetinib stood our from the library with high high binding affinity to GLP-1R and great thermal stability.

Article Title: Anti-VEGF antibodies and their uses
Article Snippet: Data were fitted using nonlinear regression with the software GRAPHPAD PRISM (GraphPad, San Diego) and the fold improvement over WT was reported as EC50 wild type/EC50 mutant. .. 10.1.2 BIAcore The binding kinetics and affinity of the antibodies for VEGF (human VEGF-A residues 27-191 of Accession # AAV38412) was determined by using a BIAcore T200 surface plasmon resonance system (BIAcore, GE Healthcare, Piscataway, N.J.). .. Coupling running buffer was HBS-EP+ running buffer (10 mM HEPES, 150 mM sodium chloride, 3 mM EDTA 0.05% P-20, pH 7.4); assay running buffer was HBS-EP+ with 300 mM sodium chloride and 0.1 mg/mL BSA (Sigma A7906).

Article Title: GB20-5A8-31, an anti-TL1A antibody for treating inflammatory bowel disease
Article Snippet: .. The binding affinity between the candidate Abs and TL1A trimers (human, cynomolgus, and rat) was evaluated using a Biacore T200 surface plasmon resonance system. ..



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